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Seth S. Joseffer, MD, FAANS, FACS



  • Gamma Knife Radiosurgery and Cyberknife


  • Neurosurgery


  • Princeton
  • Flemington

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Getting to KNOW Seth S. Joseffer, MD, FAANS, FACS


I think one thing my patients appreciate about me is that I truly get what it’s like to be sidelined by an injury. In addition to being an avid runner, I enjoy rowing, biking, playing golf, and hiking. And I’ve suffered my fair share of injuries over the years. My ability to relate to my patients and the frustration that often accompanies physical limitation makes me a better physician.

The main focus of my practice is helping people with debilitating brain or spine conditions achieve their short- and long-term goals and regain quality of life. I recognize the importance of keeping people moving and that their needs are different depending upon their stage of life. That’s why I take the time to understand how patients are limited by their condition and the goals they have following treatment. We then work together to develop an action plan that takes into account their diagnosis, overall health, and personal ambitions. These plans may include simple interventions such as physical therapy or injections, or more intricate approaches such as minimally invasive surgery or even complex spine surgery.

Degenerative spine conditions like herniated discs or pinched nerves are more common problems, but I also treat tumors affecting the brain and spine, as well as traumatic brain and spine injuries. As a life-long learner, I strive to remain at the forefront of innovation and safety. This allows me to achieve the best possible results for my patients.

It is a tremendous privilege to live and work in Princeton. As a member of this community I enjoy competing at local races—the Princeton half marathon is one of my favorites. STEM Day is another important event for my children and me. I enjoy going into the classes and talking about things like brain function or concussion. The kids really like being hands-on, so I’ll bring models of the brain or screws and rods that are used in spine reconstruction for them to work with.

Like these children, my fascination with the brain began at a young age. When I was an undergraduate student at Johns Hopkins University, I witnessed my first brain surgery. I was immediately hooked. Now I enjoy sharing my love for this field with my patients, community, and professional peers.

My practice welcomes referrals for most brain and spine disorders, and we accept most major insurance providers, as well as Medicare.

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